A Plausible “Penny” Costing Effective Treatment for Corona Virus – Ozone Therapy

Journal of Infectious Diseases and Epidemiology


Many viruses require reduced sulfhydryl groups for cell fusion and entry. Corona viruses, including SARS-CoV-2 (the cause of the condition now named coronavirus disease 2019 or COVID-19), are rich in cysteine, which residues must be intact for viral activity. Sulfhydryl groups are vulnerable to oxidation. Ozone therapy, a very inexpensive and safe modality may safely exploit this critical vulnerability in many viruses, inclusive of SARS-CoV-2.

Ozonide drugs are now postulated to possibly remedy the growing resistance of plasmodium to artemisinin, which molecule carries a rare natural oxidizing endoperoxide bridge at its active site. Industry is searching for drugs of this class [35]. Meanwhile ozone therapy, a direct method of creating endogenous ozonides, has been utilized for a century with an excellent background of researched effects, safety, and minimal costs, depending on the method and location where administered. Ozone therapy has been reported as exceptionally safe [32].

Ozone therapy is versatile and can be used for prevention and treatment of acute and chronic diseases. Our offices treat both acute (non-hospitalized cases) and chronic viral and bacterial illnesses with ozone. There have been no reports of conflicts with standard medical care, inclusive of drug therapy.

 Dosing depends on mode of application. DIV ozone generally begins with 1100 mcg ozone (20 cc of gas at 30-55 mcg of ozone per cc of gas) with increases up to 6600 mcg (120 cc gas) as needed and tolerated by the patient. Treatment time is a few to several minutes. A more recent ozone innovation is a variant of the MAH technique, called hyperbaric ozone. Two hundred ml of blood is ozonated with 200 cc medical ozone gas at 70 mcg/cc under pressure and returned under pressure.

 This constitutes a single “pass” (about 15 minutes for a treatment). A common practice in Europe and American clinics is repeating this for 10 passes at one sitting (45-90 minutes for a treatment, depending on vein “cooperation”). This will deliver 144,000 mcg ozone in a single treatment session. Our clinics are using this latter method, which appears to enhance rapid recovery from Lyme disease even in antibiotic treatment failure patients. Rowen trains physicians from around the world in this method, and has surveyed them for safety. Out of a known 4,000 “ten-pass’ treatments, there were no reported significant or lasting untoward effects due to the therapy [36]. We have observed “Herxheimer” reactions, presumably due to “die-off” of infecting organisms.

 Few in our field are not familiar with the great 1918 influenza pandemic. However, few are also aware that inexpensive intravenous hydrogen peroxide was utilized by British physician Oliver, who halved the death rate from influenza pneumonia in India [37]. Similarly, another oxidation therapy, ultraviolet blood irradiation therapy, was successfully used to cure 15 of 15 cases of viral pneumonia in hospitalized patients in the 1940s [38]. Ultraviolet energy is well accepted to destroy microorganisms, and is used as a sterilizing agent, and in air purification. Ultraviolet energy destroys cysteine in microorganisms [39].

 Ozone’s challenge is that it does not bring profit to justify private research to advance it towards regulatory agency “approval”, a process requiring tens of millions of USD. Hence, few in the medical field are aware of it, and fewer will consider “unapproved” therapy even to save lives [40]. It suffers from the “tomato effect” [41], because many of its achievements are regarded as impossible to believe. Virtually all use is in private offices, where most practitioners have no access to an institutional review board, now a requirement to gain acceptance of research for publication. Hence, advancement of ozone therapy into mainstream medicine languishes, and most patients, with no alternatives to conventional therapies, suffer.


The world already has a most inexpensive, safe, and likely effective remedy for deadly viral diseases, which exploits their redox vulnerability at critical membrane cysteine/tryptophan fusion sites. Ozone therapy could be easily deployed worldwide, even in very poor countries. With few conventional treatments for viral pneumonia, this epidemic could provide impetus to study ozone therapy very ethically under the auspices of an institution’s review board in treating, with ozone therapy, seriously ill patients, who might otherwise expire. Milder cases could also be treated to study the ability of ozone therapy to slow or halt clinical deterioration. Such study could bring ozone therapy to the forefront of all-around infectious disease management, providing answers to our growing problems with resistant infection. Governments should take notice.

Citation: Rowen RJ, Robins H (2020) A Plausible “Penny” Costing Effective Treatment for Corona Virus – Ozone Therapy. J Infect Dis Epidemiol 6:113. doi.org/10.23937/2474-3658/1510113 

Accepted: March 04, 2020: Published: March 06, 2020 Copyright: © 2020 Rowen RJ, et al.
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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